Bio-X4 Review: Promising, But Requires Consistency and Time

What Bio-X4 Gets Right

• It uses ingredients that have established benefits for digestion and metabolism.
• The product is third-party tested for quality and purity.
• The brand has a 90-day refund guarantee that allows you to test the product with little risk.
• The brand encourages taking Bio-X4 alongside a healthy diet to experience the most benefit.

Important Considerations

• You need to take the product three times a day, which may take some people time to adjust to.
• It might take several months before you notice any benefits.
• Ongoing monthly cost should be considered to make sure it fits your budget.

Bio-X4 at a Glance

Bio-X4 from Nucific is a dietary supplement designed to support various areas of the digestive system and metabolism.

It contains digestive enzymes to break down food, probiotics to improve digestion and bowel movements, and other ingredients, including green tea extract and Slimaluma, that may speed up the metabolism and prevent fat gain.

Taking Bio-X4 with each meal is designed to change how your body digests food for the better. Previous “trouble foods” can pass through your system more efficiently, so you can have regular bowel movements and fewer unpleasant symptoms like gas and bloating.

How Do I Take This Supplement?

The recommended dose of Bio-X4 is one capsule, three times per day, with meals. However, you can increase your intake to two capsules per meal, not exceeding six daily capsules.

Since it typically takes three months of regular use to witness the full benefits of Bio-X4, it's recommended to begin with a 90-day supply. Additionally, most research shows that it generally takes 2–6 weeks to start seeing results from taking probiotics.

Subscription Is Cost-Effective for Regular Use + Good Money-Back Guarantee

Bio-X4 is only available through Nucific’s website. You can’t purchase it in stores or on third-party sites. Shipping is free in the US for any purchases over $50.

If you’re unhappy with Bio-X4, you can return it for a full refund within 90 days. The terms state that even if you use up all of the product, you will get your money back if you return the empty bottle(s).

Try Bio-X4

Key Benefits of Bio-X4

Bio-X4 is designed to deliver the following health benefits:

• Manage cravings
• Weight management
• Digestive support
• Boosts metabolism

The formulation of Bio-X4 has not been tested as a whole. However, the ingredients that it contains have been individually studied. Below we compare this research against the product’s claimed benefits.

Manage Cravings

Slimaluma, a patented extract made from the popular medicinal plant Caralluma fimbriata, is traditionally known as an appetite suppressant. Some studies show that Slimaluma may help reduce unhealthy food cravings and control appetite. (1, 2, 3, 4)

Weight Management

Caralluma fimbriata and green tea extract (The green tea extract used in Bio-X4 is 50% EGCG) have studies showing that these ingredients help promote healthy weight management and reduce waist circumference. Researchers concluded that the weight loss results were likely caused by Caralluma fimbriata’s effect on controlling appetite. (3)

Green tea extract improves the body’s ability to break down body fat during steady-state exercise. Studies have shown that supplementing green tea extract leads to significant weight loss and other health benefits, such as lowering cholesterol. (5, 6, 7)

Finally, one of EGCG’s benefits includes its “anti-obesity” effects, as it increases hormones related to fat metabolism. (8)

Digestive Support

The digestive enzymes and probiotics in Bio-X4 are responsible for its digestive health claims.

Digestive enzymes indeed help break down food. However, most healthy people produce enough digestive enzymes and don’t require a supplement.

Enzymes are essential for optimal digestion, and our bodies naturally produce various enzymes, including lipase and amylase. (9) There are many different enzymes, but Bio-X4 includes amylase, bromelain, and lipase, which help break down carbohydrates, proteins, and fats.

Additionally, research shows that probiotics are generally beneficial for digestive symptoms such as diarrhea and constipation and may help with irritable bowel disease and bloating. (10) Specifically, Bio-X4 contains Lactobacillus and Bifidobacterium, two of the most well-researched probiotics. (11, 12, 13)

Boosts Metabolism

There’s evidence that green tea extract has metabolism-boosting effects, promoting fat breakdown and stimulating fat-burning by producing body heat. (14, 7)

There are no clear dosing guidelines for EGCG (Bio-X4's green tea extract). Still, studies show a wide range of doses between 100–856 milligrams for boosting metabolism. The amount of EGCG in Bio-X4 should be sufficient to offer benefits. A day’s worth of Bio-X4 contains 150–300 milligrams of EGCG (depending if you take one or two pills with each meal). (14, 6)

Bio-X4 Is Generally Safe for Most People

Bio-X4 is a generally safe supplement unlikely to cause severe or lasting side effects.

The probiotic strains found in Bio-X4 are unlikely to cause harm for healthy people. (15) However, if you are pregnant or breastfeeding or have a compromised immune system or other underlying conditions, you could be at risk of harmful effects from probiotics. (16)

Additionally, although the green tea extract used in this supplement is in safe amounts, it may interfere with certain medications. (17)

Because digestive enzymes and probiotics help your body digest food more efficiently, you may head to the bathroom more frequently.

Regarding Slimaluma, a review of several studies using the herbal extract found in this ingredient reported the main side effects as constipation, diarrhea, nausea, and rashes. (1)

Always speak with your healthcare provider before taking supplements like Bio-X4.

How Bio-X4 Compares to Alternatives

At its core, Bio-X4 is a probiotic supplement that includes digestive enzymes and several additional metabolism-boosting ingredients. Its ingredients are also third-party tested for quality and purity. These factors make Bio-X4 unique.

You can find probiotic and digestive enzyme blends for less money than Bio-X4, but they don’t have additional ingredients that Bio-X4 contains, and their probiotic content is lower. However, the other brands offer more variety and amounts of digestive enzymes.

Here’s how Bio-X4 compares to two similar products from well-known brands that combine probiotics and digestive enzymes.

Try Bio-X4

Bio-X4 contains ingredients shown to aid digestion when taken alongside a healthy diet. Try it for at least two months to see if it works for you. The brand offers a 90-day money-back guarantee.

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