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High Impact Endurance Review: Pros, Cons, and Effectiveness

Written by Lauren Panoff, MPH, RD

Published on February 23, 2021

Our Expert Rating:

4.1

About This Rating
The average rating of this product is calculated based on the evaluation of the following factors:
  • Support for Claims:4.3
  • Ingredient Safety:4.0
  • Value for the Price:4.0
  • Brand Transparency:4.0

High Impact Endurance is a supplement designed to improve energy and endurance while reducing fatigue and supporting athletic performance. While at a high price point, this product has substantial evidence behind its active ingredients and may be worth the investment for some people.

High Impact Endurance Review: Pros, Cons, and Effectiveness

Pros

  • The product is made with just two active ingredients, both of which have scientific evidence behind their intended uses
  • The product does not have any significant safety concerns for healthy people

Cons

  • The product has a high price point at over $2.00 per day
  • There is no information regarding the third-party testing company, nor does the bottle bear a seal

What Is High Impact Endurance?

High Impact Endurance, also known as Power Life Endurance, is an energy, endurance, and recovery formula made by Power Life Nutrition.

The product is claimed to provide a steady supply of energy, increase endurance levels, and reduce fatigue.

Power Life brand was created by Tony Horton, a well-known personal trainer who created the P90X home exercise program.

Evaluation of Ingredients

High Impact Endurance contains two main ingredients, which have been evaluated below based on available scientific evidence.

Hawaiian Astaxanthin

Astaxanthin is a naturally-occurring carotenoid compound. It’s responsible for the pink pigmentation of marine animals like salmon, shrimp, and lobster.

Astaxanthin is often extracted for its antioxidant and anti-inflammatory properties and used to make supplements such as this one.

Supplemental astaxanthin appears to help protect and improve the function of mitochondria, which are responsible for generating ATP energy needed to power cellular reactions in the body.

Some animal research shows that astaxanthin can help alleviate insulin resistance in skeletal muscle.

It appears to do this by activating the AMPK pathway, which signals your body to increase its uptake of glucose, inhibit glycogen storage, and look for energy from more places.

A 2006 animal study found that astaxanthin supplementation significantly increased the swimming endurance of mice, by increasing the use of fatty acids as a source of energy, compared to the control group.

Furthermore, a 2020 review of 20 studies found that astaxanthin supports muscle health by reducing oxidative stress, fueling mitochondrial regeneration, and promoting the growth of blood vessels.

It may also have therapeutic potential in the instance of sarcopenia, or age-related muscle mass loss.

Additionally, astaxanthin may be beneficial in improving fatigue.

A 2018 randomized controlled trial found that 4 weeks of astaxanthin supplementation given to 24 healthy volunteers was associated with significantly improved mental fatigue compared to placebo.

Other research suggests that its effects on fatigue are due to its ability to reduce oxidative stress and improve mitochondrial defects.

The only study I could find related to weight management was a 2006 animal study, which found that astaxanthin reduced liver weight, liver triglyceride, plasma triglyceride, and total cholesterol among obese mice fed a high-fat diet.

That being said, improved weight management could be an indirect benefit of increased endurance, energy, and muscle health for active people.

ElevATP

This is an ingredient made of blended natural peat and apple polyphenols, which has been patented by FutureCeuticals for use in this product.

A 2013 clinical study found that a single dose of ElevATP increased blood levels of ATP without increasing reactive oxygen species (ROS).

ROS are byproducts of cellular metabolism in the mitochondria that contribute to oxidative stress in the body. Your body uses ATP for energy.

A 2015 randomized controlled trial found that a once-daily supplement of ElevATP among 25 healthy, resistance-trained men helped improve skeletal muscle hypertrophy without affecting blood chemistry or fat mass.

These effects may improve athletic performance. The study was retrospectively registered as a clinical trial sponsored by MusclePharm Sports Science Institute in collaboration with VDF FutureCeuticals Inc.

Verdict on Claimed Benefits

Here is our summary of the available support for the claimed benefits of High Impact Endurance, based on the available studies:

  • Provide a steady supply of energyGold Star Evidence
  • Increase endurance levelsGold Star Evidence
  • Reduce fatigueGold Star Evidence
  • Helps with weight managementLimited Evidence

Side Effects, Safety, and Dosage

Each bottle contains 30 capsules, which is a one-month supply at one capsule per day.

The website states that this product is third-party verified to contain the ingredients claimed and in the listed amounts

However, I didn’t see any information about which third-party company this is. The bottle itself doesn’t appear to visibly bear a third-party seal.

High doses of astaxanthin may result in stomach pain, more frequent bowel movements, and a red-colored stool.

Some studies show that it may inhibit the enzyme 5-alpha-reductase and should not be taken with drugs that also hinder this enzyme.

While the health impacts are unknown, this could prevent testosterone from changing into the hormone DHT.

Cost and Where to Buy

High Impact Endurance can be purchased on the Power Life Nutrition website for:

  • 1 bottle: $64.95
  • 3 bottles: $173.85
  • 6 bottles: $329.70

At best, this comes out to $659.40 per year for someone taking it every day.

While this is a high price point, this product does have an evidence-based formulation and may be worth it for people in need of support for high-intensity activity.

The website states that the only way to get this product is through the brand website directly, which is intended to keep customer costs as low as possible.

However, I was able to find it on Amazon through the Power Life storefront, at a lower price of $52.95 for one bottle.

If you’re not satisfied, the product has a 90-day money-back guarantee with clear instructions for contacting customer service.

How It Compares

Most other similar supplements are only astaxanthin-based, as ElevATP is a patented ingredient for this product, which makes it unique.

The astaxanthin supplements cost approximately one-third as much and contain a higher dose per capsule, in some cases containing twice as much astaxanthin.

That being said, most recommended astaxanthin doses appear to be 8 mg/day or less. Not much is known about its upper limit, so more isn’t necessarily better.

The Bottom Line

High Impact Endurance is a supplement designed to improve endurance, reduce fatigue, support healthy weight management, and provide a steady supply of energy to your body.

It has a number of studies, including randomized controlled trials of humans, to back up the efficacy for most of its claims.

While it’s offered at a higher price point than other astaxanthin supplements, it contains the patented ingredient ElevATP, which has been shown to be beneficial through clinical research.

A Word from Our RD

High Impact Endurance may be beneficial for people looking to improve endurance and athletic performance.

However, improving athletic performance requires a multi-faceted approach, not just taking a dietary supplement.

A well-balanced diet that supports endurance, stress management, hydration, and adequate rest and sleep are all part of improving performance.

High Impact Endurance may be one part of the equation to help support optimal physical fitness.

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