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Mind Lab Pro Review: A Safe, High-Quality Nootropic That Is Backed by Research

By Kelsey Costa, MS, RDN

Medically Reviewed by Anastasia Climan, RDN, CD-N

Last Updated on June 3, 2022

Dietitian Rating:


About This Rating
The average rating of this product is calculated based on the evaluation of the following factors:
  • Support for Claims:4.0
  • Ingredient Safety:4.0
  • Value for the Price:4.0
  • Brand Transparency:5.0

Mind Lab Pro is a brain-enhancing supplement that claims to support six major pathways of mental performance to. If you’re looking for a nootropic with a transparent label and many ingredients backed by research, this is a great option.

Written by
Kelsey Costa, MS, RDN
Registered Dietitian
Kelsey Costa is a registered dietitian, business owner, writer, and editor with years of experience in health and wellness. She earned a Master of Science in Health and Wellness Management from Merrimack College and completed her dietetic internship with Wellness Workdays, a nationally recognized corporate wellness company.
Medically Reviewed by
Anastasia Climan, RDN, CD-N
Registered Dietitian Nutritionist
Anastasia Climan is a registered dietitian whose career progressed into public health, corporate wellness, and private practice roles. She earned a Bachelor of Science from the University of Connecticut's Coordinated Undergraduate Dietetics Program in 2011. She's led wellness initiatives on HIV/AIDS, children's health, and diabetes.
Mind Lab Pro Review: A Safe, High-Quality Nootropic That Is Backed by Research
Photo credit: iStock.com/Pyrosky


  • Most ingredients have been shown to have an important role in brain health.
  • This product is third-party tested and certified for ingredient safety and quality.


  • Several ingredients are not present in evidence-based doses in a standard serving.
  • You need to cycle (take time on and off) this supplement.

What Is Mind Lab Pro?

Mind Lab Pro is a nootropic, a dietary supplement designed to support short-term cognitive function and improve long-term brain health to improve your memory, focus, clarity, and mood.

This supplement is a product of Opti-Nutra Ltd., a premium nutrition supplement company based in the United Kingdom.

As a “Universal Nootropic”, Mind Lab Pro claims to improve aspects of brain function in all kinds of people, but especially those that live more active lifestyles.

Mind Lab Pro asserts that they are “the cleanest brain supplement ever developed”, using pure, vegan ingredients and no unnecessary additives.

What Ingredients Are Used in Mind Lab Pro?

Mind Lab Pro v4.0 is formulated with 11 all-natural, nootropic ingredients:

  • N-Acetyl-L-Tyrosine (NALT): 175 mg
  • Rhodiola rosea: 50 mg
  • Citicoline: 250 mg
  • Maritime pine bark extract: 75 mg
  • Organic lion’s mane mushroom: 500 mg
  • Phosphatidylserine: 100 mg
  • Vitamin B6: 2.5 mg (55% of the Daily Value)
  • Vitamin B9: 100 mcg (50% of the Daily Value)
  • Vitamin B12: 7.5 mcg (160% of the Daily Value)
  • L-theanine: 100 mg
  • Bacopa monnieri: 150 mg

The Benefits of Mind Lab Pro Explain

Each ingredient in Mind Lab Pro may provide benefits across multiple brain pathways.

A brain pathway, also called a neural pathway, is a collection of nerve cells (neurons) that work together to carry out a specific task, such as controlling movement or transmitting information. (1)

Below we’ll break down and discuss the befits of Mind Lab Pro.

Brain Chemistry

Nootropics in Mind Lab Pro, including N-Acetyl-L-Tyrosine (NALT) and Rhodiola rosea, are claimed to provide benefits for your brain chemistry.

Brain chemistry refers to the chemical messengers that allow neurons to communicate with each other.

These messengers, called neurotransmitters, play a critical role in brain function and are responsible for everything from mood and emotions to movement and cognition. (1)

NALT is a supplement often used to improve mental focus and concentration. It may work by increasing levels of the neurotransmitter dopamine, which is responsible for regulating mood, motivation, and pleasure. (2)

Some research indicates that supplementation with tyrosine may also help to improve cognitive performance, especially under stress or when the other neurotransmitters, dopamine or norepinephrine, are depleted. (3)

However, this effect only happens when the neurotransmitter function is normal. (3)

Additionally, there is no clinically agreed-upon effective dose of tyrosine. (3)

Rhodiola rosea is a supplement made from the Rhodiola plant.

Rhodiola rosea is thought to help improve cognitive function, alleviate stress, and improve energy levels. (4, 5, 6)

The way Rhodiola rosea works is not fully understood. However, it is considered an adaptogen.

An adaptogen is a natural product that helps the body to adapt to stress and restore balance. It does this by supporting the body’s natural defenses.

Adaptogens may help improve energy levels, increase stamina, and reduce fatigue.

Preliminary research suggests that Rhodiola rosea may be effective for some uses at doses of 100–600 milligrams (mg) of Rhodiola rosea per day. (5, 6, 7)

However, further research is needed to confirm these findings.

Mind Lab Pro contains 50 mg of Rhodiola rosea in a single serving (two capsules), which means some people may need two servings (four capsules) of Mind Lab Pro per day for a dose that falls within the range that may be effective.


There is some evidence to support the uses of N-Acetyl-L-Tyrosine (NALT) and Rhodiola rosea to support otpimal brain chemistry, but more research is needed to confirm these findings.

Brain Energy

Citicoline is one nootropic in Mind Lab Pro that is claimed to support brain energy.

Brain energy is the amount of work that the brain can do at a specific time. This mental energy comes from the food we eat and the oxygen we breathe. (8, 9)

It is used to power all of the brain’s functions, from thinking and processing information to controlling our muscles. (8, 9)

Our brain energy levels can fluctuate throughout the day, depending on our activities and how well-rested we are.

Citicoline is a natural compound that is found in the body. It is produced by the breakdown of choline, which is found in foods like eggs and meat.

Supplementation with citicoline has been shown to be an effective treatment for chronic cerebrovascular disorders and memory problems. (10)

Cerebrovascular means having to do with the blood vessels in the human brain. This includes conditions that affect these blood vessels, such as stroke, as well as problems with memory and thinking skills.

How it works is not entirely clear, but citicoline is thought to help protect cells in the brain from age-related damage and improve blood flow. This helps improve brain function and energy.

The dose of citicoline that is effective for each person may vary. However, the usual therapeutic dosage is 500–2,000 mg per day. (11)

Mind Lab Pro contains 250 mg of citicoline in a single serving (two capsules), which means some people may need two servings (four capsules) of Mind Lab Pro per day for an effective dose of citicoline.


Studies have shown that supplementation with citicoline can support brain energy, protect brain cells from age-related damage, and improve brain blood flow.

Brain Regeneration

Nootropics in Mind Lab Pro, including phosphatidylserine and organic lion’s mane mushroom, are claimed to aid in brain regeneration.

Brain regeneration is the process by which the brain repairs itself after injury.

Regeneration can happen through the growth of new neurons, the repair of damaged neurons, or the formation of new connections between neurons. (12)

Phosphatidylserine (PS) is a naturally occurring fat molecule found in high concentrations in the brain.

It has been shown to play an important role in brain function and cognitive health. In addition, PS has been shown to promote nerve cell regeneration and protect cells from damage. (13)

Exploratory research suggests that taking 300 mg of PS per day may help reduce age-related decline in brain function. (14)

Some cognitive benefits may be seen with the common dosage of 200–400 mg per day of PS. (14, 15, 16)

Mind Lab Pro contains 100 mg of PS in a single serving (two capsules), so some people may need to take two servings (four capsules) of Mind Lab Pro per day for an effective dose of PS.

Lion’s mane is an edible mushroom, also known as Yamabushitake.

This mushroom contains compounds that may help stimulate the growth of brain cells, but more human research is needed. (17)

Currently, the only human study on the use of this supplement for brain health was a small study published in 2009.

In this study, an oral dose of 1,000 mg lion’s mane (96% purity extract) was taken three times daily (a total of 3,000 mg per day) for 16 weeks. (18)

It is unknown if this is the optimal dose, but it appeared to be effective in improving mild cognitive impairment in this study. (18)

Mind Lab Pro contains 500 mg of lion’s mane mushroom in a single serving (two capsules).

Ultimately, there is not enough research to determine if Mind Lab Pro contains an effective dose of lion’s mane mushroom.


Research supports the use of phosphatidylserine (PS) for brain regeneration benefits. Lion’s mane mushroom may also help to stimulate the growth of brain cells, but more research is needed.

Brain Circulation

Maritime pine bark extract is one nootropic in Mind Lab Pro that is claimed to support brain circulation.

A potent antioxidant, maritime pine bark extract has been shown to improve brain circulation and protect the brain from damage. (19, 20, 21, 22)

This can help improve cognitive function and overall brain health.

Pycnogenol is a trademarked term used to describe maritime pine bark extract.

One way that Pycnogenol improves brain circulation is by improving blood flow to the brain, which is related to an increase in nitric oxide (NO) levels. (19)

Pycnogenol appears to be effective for improved blood flow when taken in doses of 200 mg per day. (19)

Mind Lab Pro contains 75 mg of maritime pine bark extract in a single serving (two capsules), which means some people may need two servings (four capsules) of Mind Lab Pro for an effective dose of maritime pine bark extract.


Studies have shown that supplementation with maritime pine bark extract (Pycnogenol) can improve blood flow, supporting brain circulation.

Brain Protection

Mind Lab Pro includes B-vitamins such as B6, B9, and B12 which may provide brain protection from toxins and cognitive decline.

B-vitamins are water-soluble vitamins that are present in a variety of foods and supplement forms.

The three B-vitamins in Mind Lab Pro work together to support cognitive health.

For example, vitamin B6 is important for the production of serotonin and dopamine, neurotransmitters that play a role in mood, cognition, and memory. (23)

Vitamin B9 is necessary for normal brain development and function. (23)

Vitamin B12 is essential for the maintenance of healthy brain cells. (23)

Additionally, both vitamins B6 and B12 have been shown to play a role in the development and maintenance of myelin, the protective coating that surrounds nerve cells. (24)

This means that they may help protect the brain from damage.

The recommended daily amount of vitamin B6 is 1.7 milligrams (mg), 400 micrograms (mcg) for vitamin B9, and 2.4 micrograms (mcg) for vitamin B12. (25, 26, 27)

Mind Lab Pro does not provide 100% of the Daily Value of all three B-vitamins in a single serving (two capsules).

To achieve 100% of the Daily Value of all three B-vitamins, you would need to take two servings (four capsules) of Mind Lab Pro per day.

A deficiency in any of these vitamins can lead to cognitive problems.

Vitamin B6, B9, and B12 are essential nutrients for cognitive health, but there is not enough evidence to show that these vitamins can prevent cognitive decline.

Additionally, more research is needed to determine if supplementation with these B-vitamins can improve brain health in people who are not deficient in these vitamins.


Claims about the protective effects of vitamins B6, B9, and B12 on the brain are supported by current research. However, there is limited evidence to support that supplementation with these vitamins can prevent cognitive decline.


L-theanine and Bacopa monnieri are two nootropics present in Mind Lab Pro that are claimed to enhance learning, recall memory, and brainwaves.

Brainwaves are electrical impulses that originate in the brain.

They are produced by the firing of neurons and can be measured by electrodes placed on the scalp.

Brainwaves are divided into five categories, depending on their frequency. The categories are delta, theta, alpha, beta, and gamma. (28)

Each brainwave frequency has a different effect on the mind and body. When you enhance or increase a certain frequency, you can improve specific functions, such as memory retention, focus, and relaxation. (28)

L-theanine is an amino acid found in tea and mushrooms. It is structurally similar to glutamate, a major neurotransmitter in the body.

This amino acid has been shown to increase alpha-wave activity in the brain and promote relaxation without causing drowsiness, but further research is needed to confirm these findings. (29, 30, 31)

Alpha brain waves promote calm alertness for creativity, productivity, and learning.

In most clinical research, L-theanine is taken in a dosage of 100–200 mg. (29, 30, 31, 32)

Mind Lab Pro contains 100 mg of L-theanine in a single serving (two capsules), which means one serving of Mind Lab Pro may provide an effective dose of L-theanine for some people.

Bacopa monnieri is an herb used in Ayurvedic and Traditional Chinese Medicine to enhance cognitive function.

The major active component of Bacopa monnieri includes a type of chemical produced by plants called bacosides, which protect nerve cells against damage and act as antioxidants. (33)

Much research has been done on the benefits of Bacopa monnieri for memory, attention, and other outcomes that affect learning.

A recent review of the current research found that supplementation with Bacopa monnieri may improve cognitive performance, memory, and stress levels. (34)

Bacopa monnieri is typically taken in 300 mg doses in clinical trials that have shown beneficial results. (34)

Mind Lab Pro contains 150 mg of Bacopa monnieri in a single serving (two capsules), which means you may need two servings (four capsules) of Mind Lab Pro for an effective dose of Bacopa monnieri.


There is some evidence to support the uses of L-theanine and Bacopa monnieri for enhancing brain waves, recall memory, and learning.

Support for Claimed Benefits

Below is our summary of the evidence for the claimed benefits of Mind Lab Pro based on the available research:

Brain chemistry3/5
Brain energy5/5
Brain regeneration4/5
Brain circulation5/5
Brain protection4/5

Side Effects and Safety

There are some potential side effects associated with the ingredients in Mind Lab Pro.

Doses of 300 mg per day of Bacopa monnieri have been shown to cause gastrointestinal effects, including increased bowel movements, abdominal cramps, and nausea. (35)

There is 150 mg of Bacopa monnieri in one serving (two capsules) of Mind Lab Pro, so taking two servings (four capsules) per day may result in these side effects.

N-Acetyl-L-Tyrosine (NALT) is possibly safe when taken in doses of 150 mg per kilogram of body weight per day, for up to three months. (36)

However, some may experience side effects such as headaches and fatigue at different dosages. (37)

There is 175 mg N-Acetyl-L-Tyrosine (NALT) in one serving (two capsules) of Mind Lab Pro, so taking one to two servings (four capsules) per day might result in these side effects for some people.

Those with seizure disorders, bleeding disorders, or taking blood-thinning medications should not take phosphatidylserine. (38)

If you have a known mushroom allergy, you should avoid Mind Lab Pro and other products containing lion’s mane mushroom.

Signs of an allergic reaction to lion’s mane mushroom include skin rashes and difficulty breathing. (39, 40)

In the amounts present in two to four capsules of Mind Lab Pro, negative side effects from phosphatidylserine, lion’s mane mushroom, Rhodiola rosea, pine bark extract, citicoline, B-vitamins, and L-theanine are unlikely for most people.

Mind Lab Pro is 100% vegan, free of major allergens, gluten-free, and formulated with non-GMO ingredients.

It is also free of caffeine, synthetic additives, artificial colors, and preservatives.

The only additive used in Mind Lab Pro is NuFlow Rice Concentrate, which is used to prevent the caking of ingredients.

Mind Lab Pro is third-party certified, ensuring that this product is consistent in its quality and safety.

This supplement is only meant for adults over the age of 18 and should not be taken by those who are pregnant or nursing.

Speak with your doctor before taking Mind Lab Pro to see if this supplement is safe for you.


Ingredients in Mind Lab Pro are considered safe or possibly safe but should not be taken daily for more than four weeks.

Taking Mind Lab Pro may cause mild side effects for some people, such as gastrointestinal symptoms, headache, or insomnia.

Side effects are more likely to be experienced by those taking two servings (four capsules) per day.

How to Take Mind Lab Pro

For a standard two-capsule dose of Mind Lab Pro, take one capsule in the morning before breakfast and one in the early afternoon.

You can take up to four capsules per day in times of intense cognitive demands, but you should not exceed this amount in a 24-hour period.

Individuals may start feeling effects from Mind Lab Pro after taking it consistently for two weeks, but it is recommended to be taken for at least 30 days to see full effects.

Mind Lab Pro recommends that you cycle this supplement by taking a break from this supplement regularly, such as “four weeks on, one week off” or a weekly “five days on, two days off” cycle.

How Much Does Mind Lab Pro Cost?

Mind Lab Pro is only available to purchase from the brand’s official website.

A one-month supply (30 standard servings) of this supplement is $69.00 per bottle ($2.30 per serving). 

You can also purchase a 2-month or 4-month supply from the website.

If you choose the 4-month supply, you pay for three bottles and get one bottle for free, lowering the price per bottle to $51.75 ($1.73 per serving).

Mind Lab Pro offers a money-back guarantee and an easy-to-understand return policy.

They allow you to try the product for 30 days, using up to a maximum of one bottle.

Your request to return the product must be made within 60 days of delivery. You must contact customer service via email and follow their directions to return your unopened bottles and receive your refund, minus shipping costs.


Mind Lab Pro Alternatives

There is a lack of legitimate products in the nootropic market.

Many companies are releasing products that do not have any scientific backing, causing a lot of confusion and frustration for consumers.

That being said, in addition to Mind Lab Pro, there are other legitimate nootropic brands available that offer similar natural ingredients, such as Alpha Brain and NooCube.

However, Mind Lab Pro beats the competition in label transparency or third-party certifications.

Alpha Brain

Alpha Brain claims to help support brain functions, including memory, mental speed, and focus.

This supplement is a product of Onnit Labs, Inc. It contains a few similar ingredients to Mind Lab Pro, including phosphatidylserine, Bacopa monnieri, L-tyrosine, and L-theanine.

Like Mind Lab Pro, the standard serving of Alpha Brain is two capsules. However, unlike Mind Lab Pro, Alpha Brain’s label includes proprietary blends.

A proprietary blend is a combination of ingredients, with ingredient amounts that are not disclosed to the consumer. This means that it is not possible to determine how much of each ingredient is included in Alpha Brain.

Alpha Brain can be purchased for $34.95 for 15 servings, with discounts offered when purchasing multiple bottles or a subscription.

Like Mind Lab Pro, Alpha Brain is third-party tested for safety and accuracy.


NooCube claims to offer five brain benefits, including improved focus, boosted memory, increased attention, lowered stress levels, and enhanced eye-brain connection.

NooCube also contains a few ingredients that are present in Mind Lab Pro, including vitamin B12 (2.5 mcg), L-tyrosine (250 mg), L-theanine (100 mg), and Bacopa monnieri (250 mg).

In a standard two-capsule serving, NooCube contains less vitamin B12, more L-tyrosine, the same dosage of L-theanine, and more Bacopa monnieri compared to the dosage of these ingredients in Mind Lab Pro.

NooCube is available for $59.99 for 30 servings, with savings offered on 3-month and 6-month supplies.

Unlike Mind Lab Pro, NooCube is not third-party tested for safety.

Mind Lab Pro Alpha Brain NooCube
Our Rating 4.3 3.3 Not rated
Active Ingredients Vitamin B6, Vitamin B9, Vitamin B12, Citicoline, Bacopa monnieri, Organic lion’s mane mushroom, Phosphatidylserine, N-acetyl L-tyrosine, L-theanine, Rhodiola rosea, Maritime pine bark extract L-tyrosine, Phosphatidylserine, Oat straw extract, Cat’s claw, Huperzia serrata, Bacopa monnieri, L-leucine, Pterostilbene, Huperzine A Bacopa monnieri, L-tyrosine, Cat’s claw, Oat straw extract, L-theanine, Alpha GPC, Marigold extract, Resveratrol, Pterostilbene, Vitamin B1, Vitamin B7, Vitamin B12 
Cost $1.73–$2.30/serving $1.24–$2.33/serving $0.99–$1.99/serving
Dose 2–4 pills daily 2 pills daily 2 pills daily
Claimed Benefits Focus, clarity, memory, and mood Memory, mental speed, and focus Focus, memory, attention, and stress
Third-Party Testing Yes Yes No

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The Bottom Line

Mind Lab Pro is a vegan nootropic supplement that includes many ingredients that have been shown to support short- and long-term brain health.

This supplement contains a unique formulation of safe, high-quality natural ingredients that are backed by evidence-based research and third-party testing.

In a standard two-capsule dose, not all of the nootropic ingredients in Mind Lab Pro are present in the minimum amounts that have been shown to be effective in scientific studies.

However, clinical doses of some ingredients in Mind Lab Pro can be achieved with a four-capsule dose.

If two capsules do not seem to provide you with the desired effects, you can try taking up to four capsules in a 24-hour period.

According to Mind Lab Pro, to ensure the best results, this supplement should be used in combination with healthy eating and physical activity, as part of a healthy lifestyle.

Mind Lab Pro may not provide every benefit that is claimed, but if you are in the market for a nootropic supplement, I think this product is a good choice compared to alternatives.

Before you start taking Mind Lab Pro or any other supplement, it is important to speak with your doctor to see if it’s right for you.

Additional Ways to Support Your Brain Health

Whether you decide to try nootropic supplements or not, if you want to improve your brain health through lifestyle habits, there are some things that you can do daily:

  • Make room for plant-based foods on your plate. Fruits, vegetables, and whole grains provide antioxidants that reduce inflammation and protect your brain cells from free radical damage.
  • Incorporate protein foods and dark leafy greens into your diet. These foods provide the B-vitamins that you need for the formation of neurotransmitters and other functions that are crucial to brain health.
  • If you are a vegan or vegetarian, make sure to eat foods that are fortified with vitamin B12 or consider dietary supplements.
  • Finally, make sure to practice healthy behaviors such as regular exercise, stress management, and good sleep hygiene.
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