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Nugenix Total-T Review: Pros, Cons, Ingredients, and Side Effects

Written by Emily Hirsch, MS, RD

Reviewed by Anthony Dugarte, MD 

Last Updated on April 13, 2021

Our Expert Rating:


About This Rating
The average rating of this product is calculated based on the evaluation of the following factors:
  • Support for Claims:2.0
  • Ingredient Safety:4.0
  • Value for the Price:2.0
  • Brand Transparency:3.0

There is very little scientific evidence to support the claims from Nugenix Total-T, or any other testosterone booster, of increasing testosterone levels, maximizing physical performance, and boosting libido.

Nugenix Total-T Review: Pros, Cons, Ingredients, and Side Effects


  • Offers free samples to try before you buy
  • May help prevent Vitamin B deficiencies


  • Very limited evidence to suggest this blend of nutrients will increase testosterone levels
  • Could pose potential health risks


Nugenix Total-T is a “testosterone booster” that claims to maximize strength, muscle, energy, and endurance.

This nutritional supplement also promises to spice up your love life with more passion and libido.

Testosterone is an important hormone linked to improved heart health, increased bone strength, increased libido, and improved mood.

According to research, testosterone deficiency affects 10%–40% of adult males.

Symptoms that may accompany low testosterone include fatigue, decreased lean muscle mass, irritability, low sex drive, and erectile dysfunction.

Nugenix Total-T is manufactured by Adaptive Health LLC. There are various other supplements under the Nugenix umbrella, including other testosterone supplements, multivitamins, and recovery boosters.

Evaluation of Ingredients

Vitamin B6

Vitamin B6 is a water-soluble vitamin that is essential for various biochemical reactions in the body.

Additional roles for vitamin B6 include hormone signaling, fat and carbohydrate metabolism, and manufacturing heme iron.

If you are deficient in vitamin B6, supplementation may be beneficial for your overall health.

However, there is no evidence to suggest that vitamin B6 will help increase your testosterone levels.

Vitamin B12

Vitamin B12 is an essential nutrient that plays an important role in cognitive functioning and the formation of red blood cells.

There’s little to no research suggesting that taking a vitamin B12 supplement will help increase testosterone levels.


Zinc is an essential mineral required for various enzyme reactions, immune function, and protein synthesis. Zinc can’t be stored in the body; therefore, regular dietary intake is required.

There has been some research to suggest a link between zinc and testosterone levels.

One recent study showed that low zinc levels might negatively affect men’s testosterone levels, sexual health, and fertility.

L-Citrulline Maltate

L-Citrulline Maltate is an amino acid produced by the body and is also found in food, such as watermelon.

This compound can help open veins and arteries to increase blood flow and potentially reduce blood pressure.

There is limited evidence to suggest that L-Citrulline Maltate can increase testosterone levels.

One small study suggests that L-citrulline supplementation may improve symptoms of mild erectile dysfunction in men, but additional research is needed to confirm this link. 

Fenugreek Extract

Fenugreek is an herb that has been used in alternative and Chinese medicine for thousands of years.

There are some studies linking Fenugreek to increased testosterone levels. One study found that Fenugreek supplementation decreased body fat and increased testosterone.

Another study involving 120 men found that men taking 600 milligrams of fenugreek seed extract daily for 12 weeks had improvements in sexual function and testosterone compared to the placebo group.

More research is needed to establish a more solid link between Fenugreek supplementation and increased testosterone.

Ancient Pear Extract and Apple Fruit Extract

Ancient pear extract and apple fruit extract contain antioxidants, but neither has been studied for their potential to increase testosterone levels.

Eurycoma longifolia Extract

Eurycoma longifolia is an herbal supplement that comes from a green shrub native to Southeast Asia.

One small study found that Eurycoma longifolia increased testosterone levels in older men.

However, larger-scale studies are needed to establish whether Eurycoma longifolia can effectively boost testosterone levels in men of various ages.


Boron is a trace mineral required for bone and muscle strength, cognitive functioning, and muscle coordination.

Boron also positively impacts the body’s use of estrogen, testosterone, and vitamin D

One research study suggests that boron supplementation may increase testosterone levels, but more research is needed to confirm this relationship.

Verdict on Claimed Benefits

Below is our summary of the available evidence for the claimed benefits of Nugenix Total-T based on the available research:

  • Increase energy levelsModerate Evidence
  • Increase testosteroneModerate Evidence
  • Boost libidoNo Evidence
  • Enhance muscle massNo Evidence

Dosage, Safety, and Side Effects

The recommended dosage for Nugenix Total-T is 3 capsules per day.

While many of the ingredients found in Nugenix Total-T are generally safe, it is important to note that there are health risks associated with testosterone boosters in general.

Common symptoms associated with testosterone boosters may be mild digestive discomfort.

According to recent research, testosterone boosters have the potential to cause kidney and liver abnormalities, although more research, with larger-scale studies, is needed to confirm this link.

It is always important to consult your healthcare provider before taking any supplement to ensure its safety for you.

Cost and Where to Buy

A one-month supply of Nugenix Total-T costs between $64.99 to $69.99 per bottle.

It is available directly from the company’s website and major retailers like Amazon, Walgreens, Rite Aid, and GNC.

Compared to other testosterone boosters, Nugenix Total-T is expensive.

You can find many similar testosterone boosters on online retailers like Amazon at a fraction of the cost of Nugenix Total-T.

Comparison to Alternatives

There are many testosterone boosters on the market today. Oftentimes they contain a proprietary blend of ingredients.

These proprietary blends are exclusive to the manufacturer, and the exact amount of nutrients within them is often unknown.

That being said, many testosterone-boosting supplements generally contain a similar nutritional profile.

These various vitamins, minerals, and herbs may include B vitamins, fenugreek, amino acids, antioxidants, and zinc.

An example of a similar product to Nugenix Total-T is Lean Nutraceuticals Md Certified Testosterone Booster for Men. It has a similar nutritional profile to Nugenix Total-T and costs $23.75 for a month’s supply.

Iron Brothers Testosterone Booster is another product similar to Nugenix Total-T and costs $25.97 for a month’s supply.

However, Iron Brothers Testosterone Booster also contains vitamin D. Vitamin D has shown promising results in its potential ability to increase testosterone levels in men.

Additionally, recent research has shown that vitamin D deficiency is associated with lower testosterone in young men.

The Bottom Line

Who doesn’t want to perform like a rock star at the gym and in the bedroom? Unfortunately, this ability isn’t going to be found in a testosterone-boosting supplement like Nugenix Total-T.

A review of the literature recently published in The World Journal of Men’s Health found that the research does not support the composition and claims of testosterone-boosting supplements.

There is some research to suggest that vitamin D supplementation may help to increase testosterone levels.

One study found that taking 3,000 IU of supplementation vitamin D increased testosterone levels by roughly 25%.

A Word from Our RD

If you’re looking for other natural ways to boost your energy levels, build more muscle mass, and enhance your athletic performance, look no further than your local grocery store or neighborhood gym.

Eating foods that are high in zinc may help naturally boost your testosterone levels. Foods like oysters, poultry, beans, and nuts all contain this important mineral.

Magnesium is another important mineral that may help increase your testosterone levels. Foods rich in magnesium include spinach, kale, swiss chard, nuts, seeds, and whole grains.

Eating a well-balanced diet along with regular exercise will support your desire for vitality.

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