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PhenQ Review: Hard to Justify the Higher Cost

By Emily Hirsch, MS, RD and SaVanna Shoemaker, MS, RDN, LD

Last Updated on August 4, 2023

Medically Reviewed by Natalie Olsen, MS, RDN

Dietitian Rating:


About This Rating
The average rating of this product is calculated based on the evaluation of the following factors:
  • Support for Claims:3.5
  • Ingredient Safety:4.0
  • Customer Service:3.0
  • Value for the Price:3.5

PhenQ commands a higher price without clear reasons why consumers should pay more. While there is research for some of the ingredients, we believe higher-quality and cheaper options are available.

Written by
Emily Hirsch, MS, RD
Registered Dietitian, Women's Health Specialist and GI Health
Emily Hirsch is a registered dietitian with over fifteen years of experience in the health and wellness space. She received her undergraduate degree in dietetics from the University of Rhode Island and her Masters of Science with distinction in nutrition education from California State University, Chico.
Written by
SaVanna Shoemaker, MS, RDN, LD
Registered Dietitian Nutritionist
SaVanna Shoemaker, MS, RDN, LD spent several years working in various dietetic roles and settings, including research, public health, dialysis, and acute care. She became a Registered Dietitian Nutritionist in 2013, while completing her Master of Science degree at The University of Southern Mississippi.
Medically Reviewed by
Natalie Olsen, MS, RDN, LD, ACSM-EP
Registered Dietitian, Certified Exercise Physiologist
Natalie is a registered dietitian, functional medicine practitioner and certified exercise physiologist with over 15 years experience in the health and wellness industry and holds a Master's degree in Human Nutrition and Functional Medicine through a collaborative program provided by the University of Western States and the Institute of Functional Medicine.
PhenQ Review: Hard to Justify the Higher Cost

Key Highlights (TL;DR)

  • PhenQ is a stimulant-containing, multiple-ingredient supplement designed to target several aspects of weight loss.
  • PhenQ can be used to support your active lifestyle and a healthy diet, but it’s not sustainable long-term.
  • All ingredients in PhenQ have been studied with varying degrees of evidence for weight loss benefits. However, some studies are very small in duration and participant size.
  • The strongest evidence is that Capsimax powder, caffeine, and chromium picolinate increase metabolism, burn fat, and support energy.
  • Most of PhenQ’s ingredients are in lower amounts than those used in studies.
  • Not much is known about the brand behind PhenQ. There are a high number of customer service complaints on Trustpilot.
  • PhenQ is more expensive than its alternatives, but there are not enough convincing arguments to justify the higher cost.

Things to Like About PhenQ:

  • Offers a 60-day money-back guarantee (on all purchase options)
  • Uses all-natural ingredients
  • Lower caffeine amount than other stimulant-containing weight loss supplements
  • Provides a transparent product label

Important Considerations:

  • Possible stimulant side effects due to caffeine content.
  • No third-party testing to confirm that it has what it states on the label and to indicate the purity of the ingredients
  • Customer service complaints related to not getting your order or receiving a refund

PhenQ at a Glance

The weight loss supplement market is a crowded space known for big claims, loud promises, high prices, and little robust evidence. However, what can be said for certain is that no evidence would convincingly indicate that they can provide meaningful long-term weight loss benefits.

Still, some ingredients could offer short-term weight loss benefits for people who are already following a calorie-reduced diet and an exercise program.

PhenQ, from Wolfson Brands Limited, is one of many weight loss supplements containing multiple ingredients to help address various factors contributing to weight loss. These include suppressing appetite, increasing metabolism and fat burning, promoting energy, and improving mood.

It is meant to be taken twice a day — one capsule with breakfast and one with lunch.

PhenQ makes a lot of bold claims, but upon thorough evaluation, it leaves us wanting more. We’ll unpack everything in our detailed review below.

PhenQ Ingredients and Research

Many of the ingredients in PhenQ have solid evidence to support their use for weight loss and energy, especially caffeine. However, PhenQ may not contain a large enough dose of the other ingredients to show any benefit in those aspects.

Additionally, from a big-picture perspective, it’s important to remember that this supplement’s effect on your body’s fat-burning ability and appetite regulation are very small. These weight loss benefits can be completely canceled out if you’re not eating a healthy diet and exercising.

Below we’ll break down each ingredient.

Capsimax Powder

PhenQ contains Capsimax powder (Capsicum fruit extract) from red chili peppers, which is a source of Capsaicin. In one study, taking 2 mg of capsaicin increased calorie burn without increasing appetite or calorie intake, which may be helpful for weight loss. Another study showed that taking 4 mg of Capsicum for 12 weeks helped reduce body fat more than taking 2 mg. (1, 2)

A daily serving of PhenQ contains 2 mg of capsaicin from Capsimax, which matches the amount used in the studies referenced above.

α-Lacys Reset

α-Lacys Reset is PhenQ’s specialized ingredient. This patented formula contains a combination of two amino acids: alpha-lipoic acid (ALA) and cysteine, which synergistically are supposed to aid in weight loss.

PhenQ has completed its own clinical study on α-Lacys Reset, showing that participants lost weight, reduced body fat, and increased muscle mass. However, it has no information on the number of participants, variables like food intake and exercise, and how the body fat was calculated. We were unable to retrieve a report of this study from the company, nor is it available in any scientific journal at this time.

When evaluating the effects of weight from the ingredients individually, one 24-week study found that 600 mg of alpha-lipoic acid per day was associated with greater weight loss than a placebo. (3) Another 2018 review of studies found that supplementation with alpha-lipoic acid (ALA) slightly decreased body weight and BMI. The study concluded that 1,200 mg of ALA is safe. (4)

Overall, the amount of ALA shown to be effective for weight loss is significantly higher than what is present in PhenQ since α-Lacys Reset blend amount is only 25 mg.

Regarding the research on cysteine (the other ingredient in α-Lacys Reset), a small study showed it may help reduce appetite, which may promote weight loss. (5)

Chromium Picolinate

Chromium picolinate (an essential mineral found in many foods such as meat, whole grains, and some fruits and vegetables) is a more easily absorbed form of chromium often found in dietary supplements. Chromium plays a role in carbohydrate and fat metabolism and may help reduce body fat and body weight.

Specifically, a 2019 meta-analysis found that 400 mcg of daily chromium supplementation did reduce weight, BMI, and body fat percentage. However, researchers concluded that these effects are minimal. (6, 7) Another 2018 study showed that 1000 mcg of chromium picolinate reduced appetite. (8)

PhenQ contains 40 mcg of chromium picolinate in a daily serving size, which is less than the amount used in these studies.

Caffeine Anhydrous

Caffeine anhydrous is dehydrated caffeine in the form of crystallized powder. Caffeine has been shown in many studies to boost metabolism and increase your body’s fat-burning abilities, especially during exercise.

In one study, researchers found that a moderate dose of caffeine (3 mg/kg body weight, or about 200 mg for a 150-pound/67 kg person) could increase fat burn and decrease fatigue during one hour of exercise. (9)

In another trial, researchers found that fitness drinks containing 100–140 mg of caffeine could increase energy expenditure (how many calories you burn) and fat oxidation (the body’s fat-burning process) during exercise and at rest. (10)

If taken per label instructions (2 capsules), PhenQ provides 200 mg of caffeine, which may offer some benefits.

Nopal Cactus Fiber

Copal cactus, also known as “prickly pears cactus,” is native to the Southwest United States, Spain, Italy, and South Africa. This fiber binds to dietary fat and enhances its excretion, limiting the amount of fat the body absorbs. (11)

L-Carnitine Fumarate

L-carnitine is a naturally occurring amino acid found in foods like red meat, nuts, whole grains, and green vegetables.

One study noted that a combination of 200 mcg of chromium (an ingredient also included in PhenQ) and 1000 mg of carnitine daily for 12 weeks was linked to weight loss in overweight and obese women. (12) However, PhenQ contains significantly less of these two ingredients.

Additionally, other studies have shown L-carnitine to reduce BMI, body fat, and body weight, but at doses higher than what is present in this supplement. (13, 14)

B Vitamins

PhenQ contains vitamins B3, B6, and B12. These are water-soluble vitamins that are essential for supporting energy and mood. Studies have shown that supplementation with B vitamins and other nutrients may improve energy levels, cognitive function, and mood, but only if you’re deficient in these vitamins. (15, 16, 17)


Iodine is an element that helps support the thyroid and cells, which in turn supports metabolism. Our body does not make it on its own, and should be obtained from diet and supplements. According to the National Insititute of Health, men and women ages 19 and up should get 150 mcg of iodine daily. PhenQ contains just that amount when taking 2 pills daily. (18, 19)


InnoSlim is a patented blend containing Panax notoginseng extract and Astragalus membranaceus. We contacted NuLive Science, the manufacturer of this blend, to obtain human studies and they immediately provided us with them.

One small 2022 study done on 12 people showed that after 6 weeks of supplementing Astragalus and notoginseng, the participants experienced lowered fast glucose levels by 10–20%, significantly lowered HDL cholesterol (bad cholesterol), and a significant increase in AMPK levels. (20)

AMPK is a protein that helps the body keeps its energy levels balanced. When AMPK is activated, it may help the body burn fat and sugar energy as well as affect satiety. This may all help support weight management. Other studies confirm that ​​notoginsenosides, one of the main active compounds in Panax notoginseng, can help with weight management by activating AMPK. (21, 22)

Safety Considerations and Side Effects

Most of the ingredients in PhenQ are safe when the supplement is taken as directed. However, the caffeine content can be a concern.

If you take two servings of PhenQ per day as recommended, the supplement provides 150 mg of caffeine, which is around 1.5 cups of coffee daily.

If you’re already getting caffeine from other sources, such as soda, coffee, tea, or energy drinks, you should be careful with PhenQ. Some people may experience jitters, headaches, nausea, anxiety, and an increased heart rate from excessive caffeine intake.

We confirmed with the company that PhenQ is not third-party tested. The company did say that its supplement is manufactured in an FDA-approved facility. However, that means that they registered with the FDA, which is a requirement for all supplements manufactured in the U.S. This still does not test the contents of the supplements for safety.

Certain ingredients in PhenQ may interact with medications, especially iodine.

If you have any underlying medical issues, including hyperthyroidism or thyroid autoimmunity, consult your physician before taking this supplement.

How Much Does PhenQ Cost?

PhenQ is only available on the brand’s official website at the following prices:

  • 1 Bottle: $70
  • 3 Bottles: $140 ($46.66/bottle)
  • 5 Bottles: $210 ($42/bottle)

The company offers a 60-day money-back guarantee minus shipping if you return any unused portion of your product within 67 days of receiving it. They also offer free US shipping on all orders.

Purchase PhenQ

How PhenQ Compares to Alternatives

For an accurate comparison to PhenQ, we selected two stimulant-containing weight loss supplements that use a multi-ingredient formula to target several weight loss factors, including controlling appetite, increasing metabolism, burning fat, and promoting energy.

Here’s a summary of how PhenQ compares, followed by our insights:


Transparent Labs Fat Burner

Legion Phoenix Fat Burner


Suppress appetite, increases metabolism and fat burning, promotes energy, improves mood

Suppresses appetite, increases metabolism and fat burning, promotes energy and focus

Controls hunger and cravings, increases metabolism and fat burning, promotes focus


B vitamins, Iodine, Chromium picolinate, L-carnitine, InnoSlim®, Caffeine anhydrous, Capsimax powder, α-Lacys reset, Nopal cactus, Black pepper extract

Green tea leaf extract, Forslean, Natural caffeine (from green coffee bean), L-theanine, Red pepper extract, Black pepper extract

Vitamin B6 and B12, Iodine, Caralluma fimbriata, Forskolin, Caffeine anhydrous, 5-HTP, L-DOPA, Grains of paradise, Fucoxanthin, Black Ginger


Strongest evidence for Capsimax Powder to increase metabolism and burn fat. The other ingredients are in lower doses than were used in studies or the studies are very small.

Strongest evidence for green tea leaf extract and ForsLean to suppress appetite, increase metabolism, and burn fat. Transparent label shows effective doses of ingredients.

Strongest evidence for Caralluma fimbriata and forskolin to suppress appetite, increase metabolism, and burn fat. Transparent label shows effective doses of ingredients.

Safety Concerns

Possible stimulant side effects due to caffeine content. Iodine may interact with some medications.

Possible stimulant side effects due to caffeine content. Forskolin may lower blood pressure or increase heart rate.

Possible stimulant side effects due to caffeine content. Forskolin may lower blood pressure or increase heart rate.

Daily Dose

1 capsule twice per day (2 total)

2 capsules twice per day (4 total)

3 capsules in the morning (3 total)

Total Caffeine Amount

150 mg

250 mg

200 mg

Regular Price

$69.99 (30-day supply)

$54.99 (30-day supply)

$49.99 (30-day supply)

Cost per Day




Return Policy

60-day returns (minus shipping), no need to ship back empty bottles.

30-day returns on unopened products, or store credit on opened products

30–90 day money-back guarantee, including open bottles, no need to ship it back

Brand Reputation




Testing and Certification

No information provided

Third-party tested, Certificates of analysis and composition provided

Third-party tested, Certificate of analysis provided, NSF-certified facilities


Shop from PhenQ Shop on Transparent Labs Shop on Legion Athletics

How to Choose

For starters, let’s first identify how these products are similar:

  • All three contain stimulants in varying dosages in the form of caffeine.
  • The three brands provide a transparent label listing all ingredients and amounts.
  • The three products have unique formulas, but none have been clinically studied, so there is no evidence that one is more effective than the other.
  • Despite what weight loss brands claim in their marketing, there is no evidence showing that any single ingredient can contribute to significant long-term weight loss. At best, some ingredients can promote short-term weight-loss benefits to people already following a calorie-reduced diet and exercise program.

Now, let’s proceed to what separates the three products apart to see how PhenQ stacks up across various factors:

  • Ingredients: Each product uses ingredients that have been individually studied with varying degrees of evidence for their safety and effectiveness. And although there is research to back up the claims of PhenQ’s ingredients, most of them are provided in significantly lower doses than what was used in studies, suggesting that PhenQ may not provide the same results. On the other hand, Transparent Labs and Legion Athletics offer most of the key ingredients in the same doses used in studies, making them a better pick.
  • Safety: Even though PhenQ is claimed to be safe by its manufacturer, weight loss supplements generally come with the risk of side effects, most of which are related to their caffeine content. However, PhenQ contains the lowest amount of caffeine, thus reducing these risks.
  • Third-Party Testing and Certification: It’s important to buy from brands that invest in third-party testing and provide certification to ensure that the supplement contains what is said on the label and is not contaminated with bacteria, heavy metals, and pesticides. PhenQ provides no information regarding third-party testing, while Transparent Labs and Legion Athletics do, making them higher-quality supplements.
  • Brand Reputation: Besides the general marketing lingo, there are not many details about Wolfson Brands, the manufacturer of PhenQ. However, this is a common occurrence among many weight loss supplement manufacturers. Once again, Transparent Labs and Legion Athletics do a better job showcasing the people and the philosophy behind the brand. Furthermore, there are quite a few customer service complaints in PhenQ customer reviews on Trustpilot. And even though every company will have some customer service complaints, including Transparent Labs and Legion Athletics, in the case of PhenQ, it is above average, creating an area of legitimate concern.
  • Cost: PhenQ is considerably more expensive than Transparent Labs and Phoenix. However, based on our research, we do not see what warrants the higher price. If you don’t mind paying more upfront, you can buy PhenQ’s 3-bottle or 5-bottle package, making the price per bottle in line with the other brands. Still, based on the other factors above, we believe Transparent Labs and Phoenix offer more value for the price.


If you are already following a calorie-reduced diet and working out, a weight loss supplement can provide some extra edge to help you achieve your weight loss goal. We recommend going with Transparent Labs Fat Burner or Legion Athletics Phoenix, the brands that provide ingredients in effective amounts and offer more transparency about the quality of their products.

Tip: Other options worth considering are stimulant-free fat burners, glucomannan supplements, or intermittent fasting.

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At WellnessVerge, we only use reputable sources, including peer-reviewed medical journals and well-respected academic institutions.

  1. Acute administration of capsaicin increases resting energy expenditure in young obese subjects without affecting energy intake, appetite, and circulating levels of orexigenic/anorexigenic peptides - PubMed:
  2. Capsaicinoids supplementation decreases percent body fat and fat mass: adjustment using covariates in a post hoc analysis - PMC:
  3. A Randomized Controlled Trial of Long-Term (R)-α-Lipoic Acid Supplementation Promotes Weight Loss in Overweight or Obese Adults without Altering Baseline Elevated Plasma Triglyceride Concentrations - PubMed:
  4. Alpha-lipoic acid supplement in obesity treatment: A systematic review and meta-analysis of clinical trials - PubMed:
  5. l-cysteine suppresses ghrelin and reduces appetite in rodents and humans - PMC:
  6. A meta-analysis of the effect of chromium supplementation on anthropometric indices of subjects with overweight or obesity - PubMed:
  7. Chromium - Health Professional Fact Sheet:
  8. Effects of Chromium Picolinate on Food Intake and Satiety - PMC:
  9. Caffeine increases whole-body fat oxidation during 1 h of cycling at Fatmax - PubMed:
  10. The acute effects of thermogenic fitness drink formulas containing 140 mg and 100 mg of caffeine on energy expenditure and fat metabolism at rest and during exercise - PubMed:
  11. Effects of Cactus Fiber on the Excretion of Dietary Fat in Healthy Subjects: A Double Blind, Randomized, Placebo-Controlled, Crossover Clinical Investigation - PMC:
  12. Effects of Chromium and Carnitine Co-supplementation on Body Weight and Metabolic Profiles in Overweight and Obese Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial - PubMed:
  13. Effects of l-carnitine supplementation on weight loss and body composition: A systematic review and meta-analysis of 37 randomized controlled clinical trials with dose-response analysis - PubMed:
  14. The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials - PubMed:
  15. B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review - PMC:
  16. Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence - PMC:
  17. A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and ‘At-Risk’ Individuals - PMC:
  18. Iodine - Consumer:
  19. Iodine | The Nutrition Source | Harvard T.H. Chan School of Public Health:
  20. Anti-hyperglycemic and anti-hyperlipidemic activities of Radix Astragali and Panax notoginseng extract in human participants: A randomized, double-blind, crossover clinical trial.:
  21. Hypothalamic AMPK as a Regulator of Energy Homeostasis - PMC:
  22. Effect of Panax notoginseng Saponins and Major Anti-Obesity Components on Weight Loss - PMC: