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Fatty15 Review: Can This Supplement Help You Age Better?

By Erika Thiede, MS, RDN, CSSD

Medically Reviewed by Natalie Olsen, MS, RDN, LD, ACSM-EP

Published on July 13, 2022

Dietitian Rating:

4.1

About This Rating
The average rating of this product is calculated based on the evaluation of the following factors:
  • Support for Claims:4.0
  • Ingredient Safety:4.5
  • Customer Service:4.0
  • Value for the Price:4.0

Fatty15 is a fatty acid supplement designed to make you feel healthier and age better. Research shows that supporting your cells with this newly discovered fatty acid may help you fight off aging-related conditions.

Written by
Erika Thiede, MS, RDN, CSSD
Registered Dietitian Nutritionist, Integrative and Functional Nutritionist
Erika Thiede is a Registered Dietitian Nutritionist with 10 years of experience in the field of nutrition. While at USC, Erika worked alongside the head sports dietitian, allowing her to realize her true passion was in the field of nutrition and dietetics. Erika completed her master’s degree at Loma Linda University and became a registered dietitian in 2015.
Medically Reviewed by
Natalie Olsen, MS, RDN, LD, ACSM-EP
Registered Dietitian, Certified Exercise Physiologist
Natalie is a registered dietitian, functional medicine practitioner and certified exercise physiologist with over 15 years experience in the health and wellness industry and holds a Master's degree in Human Nutrition and Functional Medicine through a collaborative program provided by the University of Western States and the Institute of Functional Medicine.

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Fatty15 Review: Can This Supplement Help You Age Better?
Photo credit: iStock.com/kupicoo

Pros

  • A vegan source of a potential essential fatty acid called pentadecanoic acid, also known as C15:0.
  • Strong evidence behind the ingredients
  • No taste or smell.
  • Eco-friendly and sustainable.
  • Vegan, dairy-free, gluten-free, and free of preservatives.

Cons

  • There is no third-party testing seal.
  • May be expensive for some people.

Aging is inevitable, but the way we age may be affected by the strength and health of our cells. Fragile and damaged cells may leave us more susceptible to illness and aging. (1)

While a healthy diet and exercise are critical steps to maintaining vital cells, scientists have recently discovered a new nutrient that may aid in keeping our cells youthful.

This fatty15 review discusses the story behind the brand, the evidence and safety of its formula containing the fatty acid, how it may help you feel healthier and age better, and its safety to help you decide if it’s the right choice.

What Is Fatty15?

Fatty15 is a fatty acid C15:0 supplement that can support cellular health, boost your mitochondria, and ward off age-related illness.

An essential fatty acid refers to fatty acids that the body cannot make and are crucial to getting into the diet.

Fatty15 supplement is designed to replenish the body with this critical fatty acid that has been declining from the modern diet for years.

Our primary dietary source of fatty acid C15:0 is whole-fat dairy products. However, even in butter and whole-fat milk sources, C15:0 is available in minimal amounts. (2)

These foods also contain higher even chain fatty acids, which may increase the risk of heart disease, inflammation, and type 2 diabetes. (3)

Fatty15’s unique formula offers a pure form of essential fatty acid C15:0 as a vegan-friendly dietary supplement.

Supplementation requires one pill a day, every day. It is recommended to take Fatty15 on an ongoing basis and as part of your current health regime to receive ultimate health benefits.

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How Was Fatty15 Discovered?

While observing a pod of dolphins, Founders, and life partners, Dr. Stephanie and Dr. Eric Ven-Watson may have found what points to be the first essential fatty acid in 90 years called pentadecanoic acid — or C15:0. (2)

That was the start of the idea behind Fatty15.

Dr. Stephanie Ven-Watson — a former veterinary epidemiologist — began her studies to uncover how changes in the ocean impact the dietary needs of dolphins.

The researchers tracked two groups of dolphins — a pod in San Diego, California, and a group in Sarasota, Florida.

While both groups of dolphins were relatively healthy, they found that the California pod had more aging-related conditions than the dolphins in Florida.

Those aging-related conditions, similarly to humans, led to illnesses such as diabetes, heart disease, and stroke.

Upon further investigation, researchers found that the Florida pod ate fish with higher content of fatty acid C15:0.

Does Fatty15 Work? The Science Behind Its Claims

When taken daily and coupled with a healthy diet and exercise, Fatty15 may boost cellular mitochondria, improve cellular vitality, and promote health.

Evidence supports that odd chain fatty acid C15:0 is a newly discovered essential fatty acid that strengthens cell membranes, boosts mitochondria, and improves health. (4)

Below we break down each of Fatty15’s benefits for you and how the research backs up each of them.

Boost Mitochondria

Fatty15 supplement has been shown to boost mitochondrial function. (2)

Mitochondria are the energy powerhouses — they generate most of the chemical energy needed to power our cell’s critical functions.

A decline in mitochondrial quality and function has been associated with aging and correlates with age-related diseases. (5)

Research has found that individuals supplemented with C15:0 experienced repaired mitochondrial function and decreased risk for heart disease. (2)

In addition to optimal fatty acid intake, physical exercise is also crucial to mitochondria health. (6)

When coupled with a balanced exercise routine, Fatty15 may help combat the age-related decline in mitochondrial function.

Summary

A decline in mitochondrial health is linked to aging and aging-related disease. Studies have found that intake of fatty acid C15:0 improves mitochondrial function. When coupled with exercise, Fatty15 may enhance mitochondrial function.

Improves Cellular Health

Fatty15 supplement offers a pure and potent source of fatty acid C15:0.

Similar to mitochondria, a cell loses its ability to function over time.

Additionally, our cells become more at risk for damage as we age. (7)

As parts of the protective outer layer of the cell, fatty acids play a critical role in keeping the cell healthy. (2)

Research has shown that supplementation of fatty acid C15:0 strengthens cellular stability, protecting our cells from age-related wear and tear. (2)

The reality is that we age because our cells do, and because our body is made up entirely of cells, protecting our cells the best we can is critical to aging well.

While exercise, adequate sleep, and a healthy and varied diet are essential components of longevity, fatty acids — such as C15:0 — may aid in slowing the age-related breakdown of our cells.

Summary

Our body is made up of cells, so keeping our cells healthy is critical to health and aging well. Research supports the intake of fatty acid C15:0 in strengthening cellular health. Fatty15 offers a pure and potent source of C15:0.

Promotes Mind and Body Health

Stronger cell membranes make both you and your cells more resilient.

When coupled with a varied diet rich in omega-3s, Fatty15 can increase the intake of fatty acid C15:0 and promote mind and body health.

Research supports that a higher intake of C15:0 is associated with a decreased risk of obesity, inflammation, cardiovascular disease, type 2 diabetes, metabolic syndrome, and other health conditions. (2)

In a 14-year study involving over 14,000 people, increased intake of odd chain fatty acids — such as C15:0 — was associated with lower mortality in men and women. (2)

Additionally, clinical studies have identified that fatty acid C15:0 has similar properties to bupropion — a compound used to treat depression and other mood disorders. (8)

Further research found a link between intake of C15:0 and a reduction in anxiety. (8)

Intake of omega-3s alongside C15:0 may be a more natural approach to supporting mental health.

Food sources of omega-3 include:

  • Fatty fish — such as salmon, mackerel, and tuna
  • Nuts and seeds — such as flaxseeds, chia seeds, and walnuts
  • Oils — such as flaxseed oil and canola oil

Food sources of C15:0 include: (2)

  • Whole-fat milk
  • Butter
  • Some marine and freshwater fish

Keep in mind that food sources contain minimal amounts of C15:0, and vegan sources of C15:0 are much less available.

Summary

While there are food sources of C15:0, the fatty acid is present in low amounts and is much less available in vegan sources. When coupled with a healthy diet rich in omega-3s, Fatty15 may increase the intake of C15:0 and promote a healthy mind and body.

Support for Claimed Benefits

Below we rate each claimed benefit of Fatty15 against current scientific research behind its ingredients:

Boost cellular mitochondria4/5
Improve cellular vitality4/5
Promote mind and body health4/5

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Is Fatty15 Safe?

Fatty15 is safe for most people — including children ages 4+, pregnant women, and nursing moms.

There are no medication interactions with Fatty15 — however — it is always best to speak to your medical provider before beginning any supplementation.

Fatty15 is vegan, dairy-free, gluten-free, and free of preservatives, fillers, corn, soy, and artificial colors.

Keep in mind though that Fatty15 is not yet third-party tested. Third-party testing helps ensure the accuracy of the product’s label and that it is not contaminated.

Cost and Where to Buy

Fatty15 can be purchased online through the company’s official site at fatty15.com.

Purchase options include:

Fatty15 offers a 100% satisfaction guarantee with your first order for the first 30 days — you can request a full refund if you are unsatisfied with your product within 30 days of your purchase.

You can also cancel your subscription at any time and be refunded if you cancel before your next shipping date.

Once you purchase, you will receive a starter kit — including your reusable glass storage bottle, your supply of capsules, and an educational insert.

You will receive supplement refill pouches directly to your door for future orders.

A 30-day supply of Fatty15 with a subscription is comparable to other omega-3s.

Fatty15 offers a convenient and eco-friendly method for purchase through their subscription service and reusable capsule bottle.

How Fatty15 Compares to Alternatives

Fatty15 supplement is truly unique as a one-of-a-kind vegan-friendly C15:0 fatty acids supplement.

There are no other supplements on the market that contain the C15:0 fatty acids, but the most comparable products include other fatty acids — like polyunsaturated fatty acids.

Examples include Mary Ruth’s Omega 3-6-7-9 supplement and Nordic Naturals Optimal Omega.

Mary Ruth’s Omega 3-6-7-9

Mary Ruth’s Organics offers an omega vegan gummy vitamin that includes omega fatty acids 3, 6, 7, and 9.

This supplement is suitable for all ages and is non-GMO, vegan, dairy-free, gluten-free, soy, and corn-free.

While the supplement does not contain odd chain fatty acid C15:0 it provides the health benefits of other essential fatty acids.

Omegas 3, 6, 7, and 9 are essential fatty acids for cardiovascular health.

Mary Ruth’s Organic Omega supplement is available as:

  • One-time purchase: $33.95
  • Monthly subscription: $30.56

Summary

If you are looking for a comprehensive blend of vegan omegas, Mary Ruth’s offers a high-quality and affordable option. It can be taken alongside Fatty15 for a well-rounded intake of essential fatty acids.

Nordic Naturals Ultimate Omega

Nordic Naturals is a reputable supplement brand, well regarded for its omega-3 products.

Their Ultimate Omega product offers a high dose of omega-3 made exclusively from 100% wild-caught sardines and anchovies.

Their product is non-GMO and third-party purity tested.

Since supplements are not monitored by the FDA, third-party testing is beneficial in confirming the potency and purity of a product.

Additionally, research supports omega-3 supplementation for cardiovascular and anti-inflammatory benefits. (9)

The Ultimate Omega supplement is available in soft gels or liquids and can be purchased for:

  • One-time purchase: $27.95
  • Monthly subscription: $25.16

Summary

Nordic Naturals is an excellent supplement for omega-3 that can be taken in addition to Fatty15 as both offer different health benefits.

Quick Comparison

Fatty15 Nordic Natural Mary Ruth’s
Non-GMO
Vegan
Vegetarian
Gluten-Free
Contains C15:0 Fatty Acid
Third-Party Tested
Subscription Only

Frequently Asked Questions

Why is Fatty15 only available as a subscription?

Fatty15 is only available as a subscription because it is recommended to be taken on an ongoing basis to feel the benefits.

Additionally, a growing body of evidence supports fatty acid C15:0 intake as an essential fatty acid.

You can cancel your subscription at any time and request a full refund within 30 days of purchase if you are unsatisfied with the product.

What if I currently take an omega-3 fatty acid supplement?

There are additional benefits to taking Fatty15. Evidence supports that both C15:0 — the ingredient in Fatty15 — and omega-3 fatty acids can improve health. You can take both together to increase your intake of essential fatty acids.

Does Fatty15 have any flavor or taste?

No, it is a pure powder with no additives, and it has no flavor or taste.

Can I take Fatty15 with other vitamins?

Yes, Fatty15 was created to complement your diet and current health regime.

No specific reactions between Fatty15 and other supplements or vitamins have been identified.

However, it is always best to speak to your healthcare provider before beginning any supplement regimen.

The Bottom Line

Fatty15 is a newly discovered fatty acid supplement supported by research as the first essential fatty acid found in 90 years that may help you with healthy aging.

Research supports the benefits of Fatty15’s active ingredient, odd chain fatty acid C15:0, in cellular health, mitochondrial health, and decreasing the risk of chronic illness.

Fatty15 offers a pure and vegan source of fatty acid C15:0 — which may not be widely available in the average diet.

While a healthy diet and lifestyle are critical to aging well, Fatty15 may offer a convenient way to increase your intake of fatty acid C15:0 and offer the health benefits of this odd chain fatty acid.

Therefore, Fatty15 may be worth trying.

Get Started With fatty15

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At WellnessVerge, we only use primary references for our articles, including peer reviewed medical journals or well-respected academic institutions.

  1. Does cellular senescence hold secrets for healthier aging? | National Institute on Aging:
    https://www.nia.nih.gov/news/does-cellular-senescence-hold-secrets-healthier-aging
  2. Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential? | Scientific Reports:
    https://www.nature.com/articles/s41598-020-64960-y
  3. Even- and odd-chain saturated fatty acids in serum phospholipids are differentially associated with adipokines - PMC:
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446160/
  4. C15:0 & Your Health:
    https://www.seraphinatherapeutics.com/yourhealth.html
  5. The Mitochondrial Basis of Aging - PMC:
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779179/
  6. Frontiers | Physical Exercise: A Novel Tool to Protect Mitochondrial Health | Physiology:
    https://www.frontiersin.org/articles/10.3389/fphys.2021.660068/full#:~:text=Indeed%2C%20physical%20exercise%20benefits%20are,et%20al.%2C%202019).
  7. Lipid peroxidation in cell death - PMC:
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319403/
  8. Broader and safer clinically-relevant activities of pentadecanoic acid compared to omega-3: Evaluation of an emerging essential fatty acid across twelve primary human cell-based disease systems | PLOS ONE:
    https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0268778
  9. Omega-3 Fatty Acids and Heart Health | Circulation:
    https://www.ahajournals.org/doi/10.1161/circulationaha.114.015176